Phosphopantetheine attachment site

WebDefinition: Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP) as part of the process of fatty acid biosynthesis. ID: GO:0000036 Synonyms: Articles referencing this term. Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork ... WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier … Hei Sook Sul, ... Li Chen, in Progress in Nucleic Acid Research and Molecular …

AmiGO 2: Term Details for "acyl carrier activity" (GO:0000036)

WebMay 28, 2010 · The amino acid sequence of NDRG1/Cap43 has been reported to bear a phosphopantetheine attachment site, an α/β hydrolase fold and three tandem repeats [15], [19], as well as a few sites that are phosphorylated by SGK [20] (Fig. 1 A). Western blotting revealed that NDRG1/Cap43 protein had several bands with different mobilities, including … Web4'-Phosphopantetheine C11H23N2O7PS CID 115254 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ... chillicothe health clinic https://vikkigreen.com

Cloning and Functional Analysis of Three Diacylglycerol ... - PLOS

WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier proteins (PCPs), also termed thiolation (T) domains’ – during the biosynthesis of fatty acids (FAs) (use ACPs) ( Scheme 23 ), polyketides (PKs) (use ACPs) ( Scheme … WebJan 17, 2024 · Among the 7 domains, the acyltransferase domain and phosphopantetheine attachment site showed the highest number of hydrogen bonds with gallic acid, i.e., 7/6 and 3/1 in hexanoic acid, respectively. According to our findings, gallic acid has a stronger binding affinity in these two domains than hexanoic acid since GA needs less binding … WebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Definition: Interacting selectively and non-covalently with the attachment site of the … chillicothe health department maternity

Acyl carrier protein DrugBank Online

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Phosphopantetheine attachment site

PhytoMine: GOTerm GO:0000036 ACP phosphopantetheine attachment site …

WebAcp phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Pfam Domain Function. PP-binding ; Transmembrane Regions Not Available Cellular … Phosphopantetheine, also known as 4'-phosphopantetheine, is a prosthetic group of several acyl carrier proteins including the acyl carrier proteins (ACP) of fatty acid synthases, ACPs of polyketide synthases, the peptidyl carrier proteins (PCP), as well as aryl carrier proteins (ArCP) of nonribosomal peptide synthetases (NRPS). It is also present in formyltetrahydrofolate dehydrogenase.

Phosphopantetheine attachment site

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WebSep 1, 2000 · Motifs I and III have been associated with ATP-binding and hydrolysis activities, respectively, since motif X contains a conserved serine to which a 4′-phosphopantetheine cofactor is very probably attached [ 3 ].

WebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process / acyl binding / lipid binding / phosphopantetheine binding Processes fatty acid biosynthetic process / lipid A biosynthetic process / lipid biosynthetic process / response to drug Components cytoplasm / cytosol General Function http://amigo.geneontology.org/amigo/term/GO:0000036

http://amigo.geneontology.org/amigo/term/GO:0000036 WebAug 16, 2024 · Most chemical modifications made to proteins within cells occur after the protein is synthesized in a process called translation. The resulting chemical changes are …

WebThe human NDUFAB1 protein contains a phosphopantetheine attachment site (DLGLDSLDQVEIIMAM), unique for acyl carrier proteins, and an EF-hand calcium binding …

WebApr 26, 2024 · In addition, it showed a close relationship with the phosphopantetheine attachment site protein (IPR006162) and acyl carrier protein of super family SSF47336 (IPR009081). It also shares similarities with the peptide chains of IPR020806 polyketide synthase, phosphopantetheine-binding domain, and others including IPR020845, … gracehillvision altman mgmtWebNov 13, 2013 · 4ihh: Chasing acyl carrier protein through a catalytic cycle of lipid A production. grace hill vision drucker and falkWebDec 6, 2013 · For NRPS, the domains are: adenylation (A), condensation (C), oxidation (Ox), thioesterase (Te) and 4-phosphopantetheine attachment site (PP). Figure 3. Alignment of the PKS/NRPS cluster at genomic coordinates of 3092397–3133943 in D. solani D s0432-1 with the two closest homologs in D. zeae Ech586 and T. turnerae T7901. The improved ... chillicothe hedrick medical centerWebDownload scientific diagram Phylogenetic analysis of CARs. A) Domain organization of CAR sequences: adenylation domain (PFam PF00501), phosphopantetheine (PP) … gracehillvision sign in capstoneWebOct 1, 2024 · Genome sequencing, comparative genomic analysis, and gene disruption of Streptomycessp. SYP-A7193 showed that the inthomycin biosynthetic gene cluster (itm) belonged to the hybrid polyketide synthase (PKS)/nonribosomal peptide … gracehillvision slnusbaumWebPhosphopantetheine attachment site Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where … chillicothe helping handsWebPhosphopantetheine attachment site Provide feedback. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. chillicothe herrnstein field