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Shoc2 protein

WebSHOC2, leucine rich repeat scaffold protein OMIM: 602775, Gene2Phenotype. 16 panels Panel Reviews Mode of inheritance Details; Filter panels. 16 panels Green SHOC2 in IUGR … WebSHOC2 is a scaffolding protein that harbors multiple leucine-rich repeats in tandem and is an upstream positive regulator of growth factor-dependent MAPK/ERK signaling. …

NM_007373.4(SHOC2):c.4A>G (p.Ser2Gly) AND Noonan syndrome …

Web13 May 2024 · protein folding GO:0050807 regulation of synapse organization GO:0032273 positive regulation of protein polymerization GO:0048857 neural nucleus development GO:1903779 regulation of cardiac conduction calcium-ion regulated exocytosis GO:0046785 microtubule polymerization GO:1903829 positive regulation of cellular protein localization … WebShoc2/SUR-8 positively regulates Ras/ERK MAP kinase signaling by serving as a scaffold for Ras and Raf. Here, we examined the role of Shoc2 in the spatio-temporal regulation of Ras by using a fluorescence resonance … doylestown pa inns https://vikkigreen.com

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Web17 Dec 2024 · SHOC2 leucine rich repeat scaffold protein (SHOC2) has been identified as a positive regulator of the Ras pathway; however, the function of SHOC2 in breast cancer … WebAs drug hunter, if we decode the 'grammar' of protein folding/misfolding, it will substantially help our… Liked by Subashchandrabose Chinnathambi I am very much excited to share our new study demonstrating the functional synaptic inputs between small-cell lung cancer (SCLC) and cortical neurons… Web订购Sur-8 抗体,可应用于免疫印迹,免疫组化检测,可与人,小鼠,大鼠样本反应,预测反应种属猪,斑马鱼,牛,马,羊,兔,狗,爪蟾,国内现货。 doylestown painting

Synthetic Lethal Interaction of SHOC2 Depletion with MEK …

Category:Structural basis for SHOC2 modulation of RAS signalling Nature

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Shoc2 protein

SHOC2 complex-driven RAF dimerization selectively contributes to …

Web24 Nov 2024 · SHOC2 is a member of the scaffold protein family and can positively regulate the Ras pathway and promote the occurrence and development of tumors by activating the Ras–Raf–ERK pathway in a variety of tumor cells . SHOC2 also could enhance the malignant potential of tumor cells, ... WebShoc2 - Rat, 4 unique 29mer shRNA constructs in retroviral untagged vector Supplier Page. ... NCBI Full Gene Name SHOC2 leucine-rich repeat scaffold protein; Add to Compare List. OriGene Technologies. 9620 Medical Center Drive # …

Shoc2 protein

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WebNM_007373.4(SHOC2):c.1660A>G (p.Ser554Gly) AND RASopathy Clinical significance: Uncertain significance (Last evaluated: Aug 18, 2024) Review status: 1 star out of maximum of 4 stars WebThe .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

WebSoc-2 suppressor of clear homolog (SHOC2) is a gene that encodes a protein that functions in the RAS/ERK MAP kinase signaling pathway as a scaffold linking Ras to downstream … WebThe scaffold protein Shoc2 is critical for transmission of the ERK1/2 pathway signals. Shoc2 accelerates ERK1/2 signaling by integrating Ras and RAF-1 enzymes into a multi-protein …

Webphospho-PDCD4 (Ser67) antibody 中文名称 磷酸化凋亡相关蛋白4抗体 别 名 PDCD4 (phospho S67); p-PDCD4 (phospho S67); Death up-regulated gene protein; Dug; H731; WebQ9UQ13 - SHOC2 - Leucine-rich repeat protein SHOC-2 - Function. Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in …

Web27 Jul 2016 · Introduction. SHOC2 (also known as SUR-8 and SOC-2) is a widely expressed protein composed almost entirely of leucine-rich repeats (LRRs), and having a region rich …

Web5 Mar 2024 · This sequence change replaces methionine with isoleucine at codon 173 of the SHOC2 protein (p.Met173Ile). The methionine residue is moderately conserved and there … cleaning rattan furnitureWeb21 Jun 2013 · Shoc2 is comprised of two main domains: the 21 leucine rich repeats (LRRs) core and the N-terminal non-LRR domain. We demonstrated that the N-terminal domain … doylestown pa is in what countyWebShoc2 is a 65 kDa protein expressed from humans to parasitic microorganisms with the 51% amino acids sequence similarity between P. falciparum and its human homolog. This … cleaning rates residentialWeb21 Mar 2024 · SHOC2 (SHOC2 Leucine Rich Repeat Scaffold Protein) is a Protein Coding gene. Diseases associated with SHOC2 include Noonan Syndrome-Like Disorder With … cleaning rat fleeceWebprotein-coding gene in the species Homo sapiens cleaning rattan garden furnitureWebthat interacts with Shoc2 is the catalytic subunit of the protein phosphatase 1 (PP1c) (Fig. 1A).9 PP1c, known for its ability to cooperate with various regulatory pro-teins,15 forms a holoenzyme with Shoc2. Owing to the high specificity of the Shoc2 interaction with M-Ras, the Shoc2-PP1c holoenzyme is targeted to stimulate Raf-1 cleaning rattan or wicker furnitureWeb• Identify SHOC2 as a critical mediator of drug resistance in a mouse model with pancreatic tumor analyzed by t-test, ANOVA, and Kaplan-Meier method. ... To achieve a good understanding of the characteristics of a protein, it is important to study its stability and folding kinetics. Investigations of protein stability have been recently ... cleaning rat poop carpet vinegar