WebWe detail the genetic and biochemical basis for the terminal amidation in thiotetroamide C biosynthesis, which involves a uniquely adapted cytochrome P450–amidotransferase enzyme pair and highlights the first oxidation–amidation enzymatic cascade reaction leading to the selective formation of a primary amide group from a chemically inert alkyl … WebSpirotetronate antibiotics, 213, 214 which exhibit a wide variety of biological activities, are a large class of natural products characterized by a tetronate unit that is spiro-conjugated …
Thiolactone - Wikipedia
WebChemical probing of thiotetronate bio-assembly Chem Commun 2. Februar 2024 Chemical ‘chain termination’ probes were utilised for the investigation of thiotetronate antibiotic biosynthesis in... WebNov 1, 2024 · Interestingly, in the biosynthesis of the thiotetronate antibiotics such as thiolactomycin and Tü 3010 ( Tao et al., 2016 ), the backbone polyketide is synthesized by a polyketide synthase (PKS) and a nonribosomal peptide synthase (NRPS) encoded in the biosynthetic operon. corgi jeans
A genomics-led approach to deciphering the …
WebChemistry Tree - Manuela Tosin Chemistry Tree: mentors, trainees, research areas and affiliations for researcher Log In Sign Up Log in to add people & connections, or click here to create an account. Save login - Forgot password Already have an account? Log in here. Login ID:Password:Re-enter:Email: WebInterrogating the bioactivities and enzymatic modification potential of a focused library of novel synthetic thiotetronate compounds. Download Full-text. Related Documents; Cited By; References; Reduction of immunoreactive properties of pea globulins as the result of enzymatic modification WebStreptomyces thiolactonus was grown from a spore stock solution (40% glycerol) on SFM agar (8 g Mannitol, 8 g soya flour, 8 g agar in 400 mL tap water adjusted to pH 7.2) or ISP2 agar3(4 g yeast extract, 4 g glucose, 10 g malt extract, 20 g agar, adjusted to pH 7.2) plates or in ISP2 liquid medium (4 g yeast extract, 4 g glucose, 10 g malt … tauti jud alba